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SMILES: Fc1ccc2c(c1)[nH]c1c2c2C(=O)NC(=O)c2c2c3cccc4CC(CCl)Cn(c34)c12

InChI Key: InChIKey=ICEBLUKQZGYHNU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6755   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1


(Homo sapiens (Human))		BDBM6755
PNG
(1,7-Annulated indolocarbazole deriv. 16-a | 24-(ch...)
Show SMILES Fc1ccc2c(c1)[nH]c1c2c2C(=O)NC(=O)c2c2c3cccc4CC(CCl)Cn(c34)c12
Show InChI InChI=1S/C24H15ClFN3O2/c25-8-10-6-11-2-1-3-14-17-19-18(23(30)28-24(19)31)16-13-5-4-12(26)7-15(13)27-20(16)22(17)29(9-10)21(11)14/h1-5,7,10,27H,6,8-9H2,(H,28,30,31)
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Article
PubMed
n/an/a 64n/an/an/an/a7.022



Lilly Research Laboratories



Assay Description
In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....

Bioorg Med Chem Lett 14: 3057-61 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.033
BindingDB Entry DOI: 10.7270/Q2KD1W3H
More data for this
Ligand-Target Pair