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SMILES: CC(C)(C)OC(=O)N1CC(C)(C1)NS(=O)(=O)c1ccc(cc1)-c1c(Cl)cc(Nc2n[nH]c(N)n2)cc1C(F)(F)F

InChI Key: InChIKey=XOZBTNIZQOSNEW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 70682   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus (HCV genotype 1a, isolate H))		BDBM70682
PNG
(US9693997, 205)
Show SMILES CC(C)(C)OC(=O)N1CC(C)(C1)NS(=O)(=O)c1ccc(cc1)-c1c(Cl)cc(Nc2n[nH]c(N)n2)cc1C(F)(F)F |$;;;;;;;;;;;;HN;;;;;;;;;;;;;;;HN;;;;;;;;;;;;$|
Show InChI InChI=1S/C24H27ClF3N7O4S/c1-22(2,3)39-21(36)35-11-23(4,12-35)34-40(37,38)15-7-5-13(6-8-15)18-16(24(26,27)28)9-14(10-17(18)25)30-20-31-19(29)32-33-20/h5-10,34H,11-12H2,1-4H3,(H4,29,30,31,32,33)
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MMDB

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PC cid
PC sid
UniChem

Similars
US Patent
n/an/an/an/a 11n/an/an/an/a



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
Plasmids expressing HCV E1 and E2 envelope proteins of GT1a H77 strain (Proc Natl Acad Sci USA 1997 94:8738-43) or GT1b Con1 strain (Science 1999 285...

US Patent US9693997 (2017)


BindingDB Entry DOI: 10.7270/Q2833Q56
More data for this
Ligand-Target Pair