BDBM70699 US9693997, 218

SMILES: COc1ccc(cc1S(=O)(=O)NC(C)(C)CO)-c1c(Cl)cc(Nc2n[nH]c(N)n2)cc1C(F)(F)F

InChI Key: InChIKey=VZGHTTDJILNNEU-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 70699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA polymerase (NS5B) (Hepatitis C virus (HCV))	BDBM70699 (US9693997, 218) Show SMILES COc1ccc(cc1S(=O)(=O)NC(C)(C)CO)-c1c(Cl)cc(Nc2n[nH]c(N)n2)cc1C(F)(F)F Show InChI InChI=1S/C20H22ClF3N6O4S/c1-19(2,9-31)30-35(32,33)15-6-10(4-5-14(15)34-3)16-12(20(22,23)24)7-11(8-13(16)21)26-18-27-17(25)28-29-18/h4-8,30-31H,9H2,1-3H3,(H4,25,26,27,28,29)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description Plasmids expressing HCV E1 and E2 envelope proteins of GT1a H77 strain (Proc Natl Acad Sci USA 1997 94:8738-43) or GT1b Con1 strain (Science 1999 285...				US Patent US9693997 (2017) BindingDB Entry DOI: 10.7270/Q2833Q56
					More data for this Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM70699 (US9693997, 218) Show SMILES COc1ccc(cc1S(=O)(=O)NC(C)(C)CO)-c1c(Cl)cc(Nc2n[nH]c(N)n2)cc1C(F)(F)F Show InChI InChI=1S/C20H22ClF3N6O4S/c1-19(2,9-31)30-35(32,33)15-6-10(4-5-14(15)34-3)16-12(20(22,23)24)7-11(8-13(16)21)26-18-27-17(25)28-29-18/h4-8,30-31H,9H2,1-3H3,(H4,25,26,27,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description Plasmids expressing HCV E1 and E2 envelope proteins of GT1a H77 strain (Proc Natl Acad Sci USA 1997 94:8738-43) or GT1b Con1 strain (Science 1999 285...				US Patent US9693997 (2017) BindingDB Entry DOI: 10.7270/Q2833Q56
					More data for this Ligand-Target Pair