BDBM7142 3-Benzamidoaminopyrazole deriv. 19::4-bromo-N-(5-cyclobutyl-1H-pyrazol-3-yl)benzamide::CHEMBL112136::N-(5-Cyclobutyl-1H-pyrazol-3-yl)-4-bromobenzamide

SMILES: Brc1ccc(cc1)C(=O)Nc1cc(n[nH]1)C1CCC1

InChI Key: InChIKey=IFWRXHDSVNMZIT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7142   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7142 (3-Benzamidoaminopyrazole deriv. 19 | 4-bromo-N-(5-...) Show SMILES Brc1ccc(cc1)C(=O)Nc1cc(n[nH]1)C1CCC1 Show InChI InChI=1S/C14H14BrN3O/c15-11-6-4-10(5-7-11)14(19)16-13-8-12(17-18-13)9-2-1-3-9/h4-9H,1-3H2,(H2,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Biology (CSIR) Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin A (unknown origin)				Eur J Med Chem 43: 2807-18 (2008) Article DOI: 10.1016/j.ejmech.2007.10.016 BindingDB Entry DOI: 10.7270/Q2MP5324
					More data for this Ligand-Target Pair				3D Structure (docked)
Cyclin-Dependent Kinase 2 (CDK2) (Homo sapiens (Human))	BDBM7142 (3-Benzamidoaminopyrazole deriv. 19 | 4-bromo-N-(5-...) Show SMILES Brc1ccc(cc1)C(=O)Nc1cc(n[nH]1)C1CCC1 Show InChI InChI=1S/C14H14BrN3O/c15-11-6-4-10(5-7-11)14(19)16-13-8-12(17-18-13)9-2-1-3-9/h4-9H,1-3H2,(H2,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Italia					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 47: 3367-80 (2004) Article DOI: 10.1021/jm031145u BindingDB Entry DOI: 10.7270/Q2RX998G
					More data for this Ligand-Target Pair				3D Structure (docked)