BDBM71465 US9694002, 496
SMILES: Fc1cc(CN2[C@H]3CC[C@@H]2CC(C3)Oc2cc(Cl)cc(OC(F)(F)F)c2)c(cc1C(=O)NS(=O)(=O)C1CC1)C1CC1
InChI Key: InChIKey=SESKKLSLNVUPLI-PMSBKCLSSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium Channel Complex (Homo sapiens (Human)) | BDBM71465 (US9694002, 496) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent | Assay Description Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc... | US Patent US9694002 (2017) BindingDB Entry DOI: 10.7270/Q24B2ZFG | |||||||||||
More data for this Ligand-Target Pair |