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BDBM74462 2-morpholinoethyl-(2-phenyl-4-tosyl-oxazol-5-yl)amine::4-(4-methylphenyl)sulfonyl-N-(2-morpholin-4-ylethyl)-2-phenyl-1,3-oxazol-5-amine::4-(4-methylphenyl)sulfonyl-N-[2-(4-morpholinyl)ethyl]-2-phenyl-5-oxazolamine::4-[(4-methylphenyl)sulfonyl]-N-[2-(4-morpholinyl)ethyl]-2-phenyl-1,3-oxazol-5-amine::MLS000051119::SMR000079015::cid_1244626

SMILES: Cc1ccc(cc1)S(=O)(=O)c1nc(oc1NCCN1CCOCC1)-c1ccccc1

InChI Key: InChIKey=OLKHAAFXCMCSDI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 74462   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 22


(Homo sapiens (Human))
BDBM74462
PNG
(2-morpholinoethyl-(2-phenyl-4-tosyl-oxazol-5-yl)am...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)c1nc(oc1NCCN1CCOCC1)-c1ccccc1
Show InChI InChI=1S/C22H25N3O4S/c1-17-7-9-19(10-8-17)30(26,27)22-21(23-11-12-25-13-15-28-16-14-25)29-20(24-22)18-5-3-2-4-6-18/h2-10,23H,11-16H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/a 7.53E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...


PubChem Bioassay (2010)


Article DOI: 10.1038/nchembio.1629
BindingDB Entry DOI: 10.7270/Q24748BK
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22


(Homo sapiens (Human))
BDBM74462
PNG
(2-morpholinoethyl-(2-phenyl-4-tosyl-oxazol-5-yl)am...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)c1nc(oc1NCCN1CCOCC1)-c1ccccc1
Show InChI InChI=1S/C22H25N3O4S/c1-17-7-9-19(10-8-17)30(26,27)22-21(23-11-12-25-13-15-28-16-14-25)29-20(24-22)18-5-3-2-4-6-18/h2-10,23H,11-16H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/a>7.94E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2CR5RTC
More data for this
Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP)


(Homo sapiens (Human))
BDBM74462
PNG
(2-morpholinoethyl-(2-phenyl-4-tosyl-oxazol-5-yl)am...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)c1nc(oc1NCCN1CCOCC1)-c1ccccc1
Show InChI InChI=1S/C22H25N3O4S/c1-17-7-9-19(10-8-17)30(26,27)22-21(23-11-12-25-13-15-28-16-14-25)29-20(24-22)18-5-3-2-4-6-18/h2-10,23H,11-16H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/a>7.94E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2VQ314Z
More data for this
Ligand-Target Pair