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SMILES: COc1cc(cc2OCOc12)[C@@H]1[C@H]2CN(C)CCC2=C(C#N)C(=N)C1(C#N)C#N

InChI Key: InChIKey=VCJRJLYGAUAEGW-MAUKXSAKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 74570   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Importin subunit alpha-1


(Homo sapiens (Human))		BDBM74570
PNG
((8S,8aR)-6-amino-8-(7-methoxy-1,3-benzodioxol-5-yl...)
Show SMILES COc1cc(cc2OCOc12)[C@@H]1[C@H]2CN(C)CCC2=C(C#N)C(=N)C1(C#N)C#N |t:21|
Show InChI InChI=1S/C21H19N5O3/c1-26-4-3-13-14(7-22)20(25)21(9-23,10-24)18(15(13)8-26)12-5-16(27-2)19-17(6-12)28-11-29-19/h5-6,15,18,25H,3-4,8,11H2,1-2H3/t15-,18+/m0/s1
PDB
MMDB

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PC cid
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Similars
PCBioAssay
n/an/an/an/a 5.69E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair