BDBM74846 (5Z)-1-(3-methylphenyl)-5-[(E)-3-phenylazanylprop-2-enylidene]-1,3-diazinane-2,4,6-trione::(5Z)-5-[(E)-3-anilinoprop-2-enylidene]-1-(3-methylphenyl)-1,3-diazinane-2,4,6-trione::(5Z)-5-[(E)-3-anilinoprop-2-enylidene]-1-(m-tolyl)barbituric acid::5-[(E)-3-Phenylamino-prop-2-en-(Z)-ylidene]-1-m-tolyl-pyrimidine-2,4,6-trione::MLS000587895::SMR000211907::cid_6862860

SMILES: Cc1cccc(c1)-n1c(O)c(C=CC=Nc2ccccc2)c(=O)[nH]c1=O

InChI Key: InChIKey=GONRQWCBXJYRET-NEHYNPCWSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 74846   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens furin (paired basic amino acid cleaving enzyme) (FURIN), mRNA (Homo sapiens (Human))	BDBM74846 ((5Z)-1-(3-methylphenyl)-5-[(E)-3-phenylazanylprop-...) Show SMILES Cc1cccc(c1)-n1c(O)c(C=CC=Nc2ccccc2)c(=O)[nH]c1=O |w:14.15,11.11| Show InChI InChI=1S/C20H17N3O3/c1-14-7-5-10-16(13-14)23-19(25)17(18(24)22-20(23)26)11-6-12-21-15-8-3-2-4-9-15/h2-13,25H,1H3,(H,22,24,26)/b11-6+,21-12+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description Official Symbol FURIN and Name: furin (paired basic amino acid cleaving enzyme) [Homo sapiens] Other Aliases: FUR, PACE, PCSK3, SPC1 Other Designati...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2H993NJ
					More data for this Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM74846 ((5Z)-1-(3-methylphenyl)-5-[(E)-3-phenylazanylprop-...) Show SMILES Cc1cccc(c1)-n1c(O)c(C=CC=Nc2ccccc2)c(=O)[nH]c1=O |w:14.15,11.11| Show InChI InChI=1S/C20H17N3O3/c1-14-7-5-10-16(13-14)23-19(25)17(18(24)22-20(23)26)11-6-12-21-15-8-3-2-4-9-15/h2-13,25H,1H3,(H,22,24,26)/b11-6+,21-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.77E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair