BDBM74997 9-chloranyl-N-cyclopropyl-5,6,7,8-tetrahydroacridine-3-carboxamide::9-chloro-N-cyclopropyl-5,6,7,8-tetrahydroacridine-3-carboxamide::MLS000731303::SMR000309578::cid_16193770

SMILES: Clc1c2CCCCc2nc2cc(ccc12)C(=O)NC1CC1

InChI Key: InChIKey=BRBXTLRLQUYYIY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 74997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM74997 (9-chloranyl-N-cyclopropyl-5,6,7,8-tetrahydroacridi...) Show SMILES Clc1c2CCCCc2nc2cc(ccc12)C(=O)NC1CC1 Show InChI InChI=1S/C17H17ClN2O/c18-16-12-3-1-2-4-14(12)20-15-9-10(5-8-13(15)16)17(21)19-11-6-7-11/h5,8-9,11H,1-4,6-7H2,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair