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BDBM74998 1-(5-bromanylthiophen-2-yl)sulfonyl-N-[2-(4-sulfamoylphenyl)ethyl]piperidine-4-carboxamide::1-(5-bromothiophen-2-yl)sulfonyl-N-[2-(4-sulfamoylphenyl)ethyl]piperidine-4-carboxamide::1-[(5-bromo-2-thienyl)sulfonyl]-N-[2-(4-sulfamoylphenyl)ethyl]isonipecotamide::1-[(5-bromo-2-thiophenyl)sulfonyl]-N-[2-(4-sulfamoylphenyl)ethyl]-4-piperidinecarboxamide::MLS000675216::N-{2-[4-(aminosulfonyl)phenyl]ethyl}-1-[(5-bromothien-2-yl)sulfonyl]piperidine-4-carboxamide::SMR000313938::cid_16002642

SMILES: NS(=O)(=O)c1ccc(CCNC(=O)C2CCN(CC2)S(=O)(=O)c2ccc(Br)s2)cc1

InChI Key: InChIKey=WLRDZJXRWNKPKI-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 74998   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))		BDBM74998
PNG
(1-(5-bromanylthiophen-2-yl)sulfonyl-N-[2-(4-sulfam...)
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)C2CCN(CC2)S(=O)(=O)c2ccc(Br)s2)cc1
Show InChI InChI=1S/C18H22BrN3O5S3/c19-16-5-6-17(28-16)30(26,27)22-11-8-14(9-12-22)18(23)21-10-7-13-1-3-15(4-2-13)29(20,24)25/h1-6,14H,7-12H2,(H,21,23)(H2,20,24,25)
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Similars
PCBioAssay
n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair