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BDBM75029 MLS000686692::N-phenyl-4-tetrazolo[1,5-a]quinoxalinamine::N-phenyl-[1,2,3,4]tetrazolo[1,5-a]quinoxalin-4-amine::N-phenyltetrazolo[1,5-a]quinoxalin-4-amine::SMR000339750::cid_1511413::phenyl(tetrazolo[1,5-a]quinoxalin-4-yl)amine

SMILES: N(c1ccccc1)c1nc2ccccc2n2nnnc12

InChI Key: InChIKey=HEROYCYJPFRIST-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75029   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))
BDBM75029
PNG
(MLS000686692 | N-phenyl-4-tetrazolo[1,5-a]quinoxal...)
Show SMILES N(c1ccccc1)c1nc2ccccc2n2nnnc12
Show InChI InChI=1S/C14H10N6/c1-2-6-10(7-3-1)15-13-14-17-18-19-20(14)12-9-5-4-8-11(12)16-13/h1-9H,(H,15,16)
PDB
MMDB

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KEGG

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antibodypedia
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PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a 2.40E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
Tankyrase 1/2


(Homo sapiens (Human))
BDBM75029
PNG
(MLS000686692 | N-phenyl-4-tetrazolo[1,5-a]quinoxal...)
Show SMILES N(c1ccccc1)c1nc2ccccc2n2nnnc12
Show InChI InChI=1S/C14H10N6/c1-2-6-10(7-3-1)15-13-14-17-18-19-20(14)12-9-5-4-8-11(12)16-13/h1-9H,(H,15,16)
PDB

UniProtKB/SwissProt

antibodypedia
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PC sid
UniChem
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



A GlaxoSmithKline Company

Curated by ChEMBL




J Med Chem 60: 5455-5471 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00137
BindingDB Entry DOI: 10.7270/Q2X350RS
More data for this
Ligand-Target Pair
Tankyrase 1/2


(Homo sapiens (Human))
BDBM75029
PNG
(MLS000686692 | N-phenyl-4-tetrazolo[1,5-a]quinoxal...)
Show SMILES N(c1ccccc1)c1nc2ccccc2n2nnnc12
Show InChI InChI=1S/C14H10N6/c1-2-6-10(7-3-1)15-13-14-17-18-19-20(14)12-9-5-4-8-11(12)16-13/h1-9H,(H,15,16)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 251n/an/an/an/an/an/a



A GlaxoSmithKline Company

Curated by ChEMBL




J Med Chem 60: 5455-5471 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00137
BindingDB Entry DOI: 10.7270/Q2X350RS
More data for this
Ligand-Target Pair