BDBM75094 (E)-2-Cyano-N-cyclohexyl-3-(5-morpholin-4-yl-furan-2-yl)-acrylamide::(E)-2-cyano-N-cyclohexyl-3-(5-morpholin-4-ylfuran-2-yl)prop-2-enamide::(E)-2-cyano-N-cyclohexyl-3-(5-morpholino-2-furyl)acrylamide::(E)-2-cyano-N-cyclohexyl-3-[5-(4-morpholinyl)-2-furanyl]-2-propenamide::MLS000779605::SMR000419788::cid_929418
SMILES: O=C(NC1CCCCC1)C(=C\c1ccc(o1)N1CCOCC1)\C#N
InChI Key: InChIKey=APSOMBILXZWHQR-WYMLVPIESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human)) | BDBM75094 ((E)-2-Cyano-N-cyclohexyl-3-(5-morpholin-4-yl-furan...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 3.85E+3 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cardiac alpha tropomyosin (Sus scrofa) | BDBM75094 ((E)-2-Cyano-N-cyclohexyl-3-(5-morpholin-4-yl-furan...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q21N7ZKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
insulin-degrading enzyme isoform 1 precursor (Homo sapiens (Human)) | BDBM75094 ((E)-2-Cyano-N-cyclohexyl-3-(5-morpholin-4-yl-furan...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 8.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2416VHJ | |||||||||||
More data for this Ligand-Target Pair |