BDBM75103 3-(1,3-benzothiazol-2-yl)-7-hydroxy-8-[(2-methyl-1-piperidinyl)methyl]-1-benzopyran-4-one::3-(1,3-benzothiazol-2-yl)-7-hydroxy-8-[(2-methylpiperidin-1-yl)methyl]chromen-4-one::3-(1,3-benzothiazol-2-yl)-7-hydroxy-8-[(2-methylpiperidino)methyl]chromone::3-(1,3-benzothiazol-2-yl)-8-[(2-methylpiperidin-1-yl)methyl]-7-oxidanyl-chromen-4-one::3-Benzothiazol-2-yl-7-hydroxy-8-(2-methyl-piperidin-1-ylmethyl)-chromen-4-one::MLS001044525::SMR000415074::cid_6184270
SMILES: CC1CCCCN1Cc1c(O)ccc2c1occ(-c1nc3ccccc3s1)c2=O
InChI Key: InChIKey=JPMBWXPVXZPNGX-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human)) | BDBM75103 (3-(1,3-benzothiazol-2-yl)-7-hydroxy-8-[(2-methyl-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | <380 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R | |||||||||||
More data for this Ligand-Target Pair |