BDBM77097 CMX157-210

SMILES: C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OCCCO

InChI Key: InChIKey=WRGYDGQSEMECID-SECBINFHSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...)	BDBM77097 (CMX157-210) Show SMILES C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OCCCO |r| Show InChI InChI=1S/C12H20N5O5P/c1-9(21-8-23(19,20)22-4-2-3-18)5-17-7-16-10-11(13)14-6-15-12(10)17/h6-7,9,18H,2-5,8H2,1H3,(H,19,20)(H2,13,14,15)/t9-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Chimerix, Inc. US Patent					Assay Description The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...				US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT
					More data for this Ligand-Target Pair