BDBM7868 2-chloro-1-(3,4-dibromothiophen-2-yl)ethan-1-one::Chloromethyl Thienyl Ketone deriv. 16

SMILES: ClCC(=O)c1scc(Br)c1Br

InChI Key: InChIKey=DVHYHNZCCIEQQA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta [7-25] (Oryctolagus cuniculus (rabbit))	BDBM7868 (2-chloro-1-(3,4-dibromothiophen-2-yl)ethan-1-one |...) Show SMILES ClCC(=O)c1scc(Br)c1Br Show InChI InChI=1S/C6H3Br2ClOS/c7-3-2-11-6(5(3)8)4(10)1-9/h2H,1H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	37
Instituto de Quimica Medica (CSIC)					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 46: 4631-3 (2003) Article DOI: 10.1021/jm034108b BindingDB Entry DOI: 10.7270/Q2DJ5CVH
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM7868 (2-chloro-1-(3,4-dibromothiophen-2-yl)ethan-1-one |...) Show SMILES ClCC(=O)c1scc(Br)c1Br Show InChI InChI=1S/C6H3Br2ClOS/c7-3-2-11-6(5(3)8)4(10)1-9/h2H,1H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of GSK3beta by liquid scintillation counting				Bioorg Med Chem 17: 6914-25 (2009) Article DOI: 10.1016/j.bmc.2009.08.042 BindingDB Entry DOI: 10.7270/Q2N29X2P
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM7868 (2-chloro-1-(3,4-dibromothiophen-2-yl)ethan-1-one |...) Show SMILES ClCC(=O)c1scc(Br)c1Br Show InChI InChI=1S/C6H3Br2ClOS/c7-3-2-11-6(5(3)8)4(10)1-9/h2H,1H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta expressed in Escherichia coli using GS-1 as substrate incubated for 20 mins by gamma[32P]ATP-based scintilla...				Eur J Med Chem 116: 281-289 (2016) Article DOI: 10.1016/j.ejmech.2016.03.035 BindingDB Entry DOI: 10.7270/Q2BP04P7
					More data for this Ligand-Target Pair