Found 4 hits for monomerid = 81367 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM81367
(PIK293)Show SMILES Cc1ccccc1-n1c(Cn2ncc3c(N)cccc23)nc2cccc(C)c2c1=O |(3.13,1.21,;3.13,2.75,;4.47,3.52,;4.47,5.06,;3.13,5.83,;1.8,5.06,;1.8,3.52,;.47,2.75,;.47,1.21,;1.8,.44,;1.8,-1.1,;.6,-2.07,;1.16,-3.51,;2.69,-3.32,;3.78,-4.41,;3.38,-5.89,;5.27,-4.01,;5.67,-2.52,;4.58,-1.43,;3.09,-1.83,;-.87,.44,;-2.2,1.21,;-3.53,.44,;-4.87,1.21,;-4.87,2.75,;-3.53,3.52,;-3.53,5.06,;-2.2,2.75,;-.87,3.52,;-.87,5.06,)| Show InChI InChI=1S/C24H21N5O/c1-15-7-3-4-11-20(15)29-22(27-19-10-5-8-16(2)23(19)24(29)30)14-28-21-12-6-9-18(25)17(21)13-26-28/h3-13H,14,25H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California, San Francisco
| Assay Description
Biochemical assay using PI3Ks and diversification of tolyl quinazolinone series. |
Chem Biol 17: 123-34 (2010)
Article DOI: 10.1016/j.chembiol.2010.01.010
BindingDB Entry DOI: 10.7270/Q2CR5RVT |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM81367
(PIK293)Show SMILES Cc1ccccc1-n1c(Cn2ncc3c(N)cccc23)nc2cccc(C)c2c1=O |(3.13,1.21,;3.13,2.75,;4.47,3.52,;4.47,5.06,;3.13,5.83,;1.8,5.06,;1.8,3.52,;.47,2.75,;.47,1.21,;1.8,.44,;1.8,-1.1,;.6,-2.07,;1.16,-3.51,;2.69,-3.32,;3.78,-4.41,;3.38,-5.89,;5.27,-4.01,;5.67,-2.52,;4.58,-1.43,;3.09,-1.83,;-.87,.44,;-2.2,1.21,;-3.53,.44,;-4.87,1.21,;-4.87,2.75,;-3.53,3.52,;-3.53,5.06,;-2.2,2.75,;-.87,3.52,;-.87,5.06,)| Show InChI InChI=1S/C24H21N5O/c1-15-7-3-4-11-20(15)29-22(27-19-10-5-8-16(2)23(19)24(29)30)14-28-21-12-6-9-18(25)17(21)13-26-28/h3-13H,14,25H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California, San Francisco
| Assay Description
Biochemical assay using PI3Ks and diversification of tolyl quinazolinone series. |
Chem Biol 17: 123-34 (2010)
Article DOI: 10.1016/j.chembiol.2010.01.010
BindingDB Entry DOI: 10.7270/Q2CR5RVT |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM81367
(PIK293)Show SMILES Cc1ccccc1-n1c(Cn2ncc3c(N)cccc23)nc2cccc(C)c2c1=O |(3.13,1.21,;3.13,2.75,;4.47,3.52,;4.47,5.06,;3.13,5.83,;1.8,5.06,;1.8,3.52,;.47,2.75,;.47,1.21,;1.8,.44,;1.8,-1.1,;.6,-2.07,;1.16,-3.51,;2.69,-3.32,;3.78,-4.41,;3.38,-5.89,;5.27,-4.01,;5.67,-2.52,;4.58,-1.43,;3.09,-1.83,;-.87,.44,;-2.2,1.21,;-3.53,.44,;-4.87,1.21,;-4.87,2.75,;-3.53,3.52,;-3.53,5.06,;-2.2,2.75,;-.87,3.52,;-.87,5.06,)| Show InChI InChI=1S/C24H21N5O/c1-15-7-3-4-11-20(15)29-22(27-19-10-5-8-16(2)23(19)24(29)30)14-28-21-12-6-9-18(25)17(21)13-26-28/h3-13H,14,25H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 237 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California, San Francisco
| Assay Description
Biochemical assay using PI3Ks and diversification of tolyl quinazolinone series. |
Chem Biol 17: 123-34 (2010)
Article DOI: 10.1016/j.chembiol.2010.01.010
BindingDB Entry DOI: 10.7270/Q2CR5RVT |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM81367
(PIK293)Show SMILES Cc1ccccc1-n1c(Cn2ncc3c(N)cccc23)nc2cccc(C)c2c1=O |(3.13,1.21,;3.13,2.75,;4.47,3.52,;4.47,5.06,;3.13,5.83,;1.8,5.06,;1.8,3.52,;.47,2.75,;.47,1.21,;1.8,.44,;1.8,-1.1,;.6,-2.07,;1.16,-3.51,;2.69,-3.32,;3.78,-4.41,;3.38,-5.89,;5.27,-4.01,;5.67,-2.52,;4.58,-1.43,;3.09,-1.83,;-.87,.44,;-2.2,1.21,;-3.53,.44,;-4.87,1.21,;-4.87,2.75,;-3.53,3.52,;-3.53,5.06,;-2.2,2.75,;-.87,3.52,;-.87,5.06,)| Show InChI InChI=1S/C24H21N5O/c1-15-7-3-4-11-20(15)29-22(27-19-10-5-8-16(2)23(19)24(29)30)14-28-21-12-6-9-18(25)17(21)13-26-28/h3-13H,14,25H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California, San Francisco
| Assay Description
Biochemical assay using PI3Ks and diversification of tolyl quinazolinone series. |
Chem Biol 17: 123-34 (2010)
Article DOI: 10.1016/j.chembiol.2010.01.010
BindingDB Entry DOI: 10.7270/Q2CR5RVT |
More data for this
Ligand-Target Pair | |
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