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BDBM81438 CDK Inhibitor, 11

SMILES: COCCNS(=O)(=O)c1ccc(Nc2nccc(n2)-c2sc(=O)n(C)c2C)cc1

InChI Key: InChIKey=WQZVTNFUNLTGDW-UHFFFAOYSA-N

Data: 5 KI

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 81438
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM81438 (CDK Inhibitor, 11) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cyclacel Limited					Assay Description Kinase assay using cyclin-dependant kinases (CDK).				Chem Biol 17: 1111-21 (2010) Article DOI: 10.1016/j.chembiol.2010.07.016 BindingDB Entry DOI: 10.7270/Q2BV7F3Q
Cyclacel Limited					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM81438 (CDK Inhibitor, 11) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cyclacel Limited					Assay Description Kinase assay using cyclin-dependant kinases (CDK).				Chem Biol 17: 1111-21 (2010) Article DOI: 10.1016/j.chembiol.2010.07.016 BindingDB Entry DOI: 10.7270/Q2BV7F3Q
Cyclacel Limited					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM81438 (CDK Inhibitor, 11) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cyclacel Limited					Assay Description Kinase assay using cyclin-dependant kinases (CDK).				Chem Biol 17: 1111-21 (2010) Article DOI: 10.1016/j.chembiol.2010.07.016 BindingDB Entry DOI: 10.7270/Q2BV7F3Q
Cyclacel Limited					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM81438 (CDK Inhibitor, 11) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cyclacel Limited					Assay Description Kinase assay using cyclin-dependant kinases (CDK).				Chem Biol 17: 1111-21 (2010) Article DOI: 10.1016/j.chembiol.2010.07.016 BindingDB Entry DOI: 10.7270/Q2BV7F3Q
Cyclacel Limited					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM81438 (CDK Inhibitor, 11) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cyclacel Limited					Assay Description Kinase assay using cyclin-dependant kinases (CDK).				Chem Biol 17: 1111-21 (2010) Article DOI: 10.1016/j.chembiol.2010.07.016 BindingDB Entry DOI: 10.7270/Q2BV7F3Q
Cyclacel Limited					More data for this Ligand-Target Pair