BDBM81466 CAS_23095-76-3::NSC_6445134::l-Chlorpheniramine

SMILES: OC(=O)C=CC(=O)Oc1ccc(Cl)cc1

InChI Key: InChIKey=ZQAHOENZMFACFJ-UHFFFAOYSA-N

Data: 8 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 81466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM81466 (CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine) Show SMILES OC(=O)C=CC(=O)Oc1ccc(Cl)cc1 |w:4.4| Show InChI InChI=1S/C10H7ClO4/c11-7-1-3-8(4-2-7)15-10(14)6-5-9(12)13/h1-6H,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB S.A. Curated by PDSP Ki Database									Mol Pharmacol 61: 391-9 (2002) Article DOI: 10.1124/mol.61.2.391 BindingDB Entry DOI: 10.7270/Q2D50KJ8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM81466 (CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine) Show SMILES OC(=O)C=CC(=O)Oc1ccc(Cl)cc1 |w:4.4| Show InChI InChI=1S/C10H7ClO4/c11-7-1-3-8(4-2-7)15-10(14)6-5-9(12)13/h1-6H,(H,12,13)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	80.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by PDSP Ki Database									J Pharmacol Exp Ther 302: 328-36 (2002) Article DOI: 10.1124/jpet.302.1.328 BindingDB Entry DOI: 10.7270/Q2JQ0ZK1
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM81466 (CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine) Show SMILES OC(=O)C=CC(=O)Oc1ccc(Cl)cc1 |w:4.4| Show InChI InChI=1S/C10H7ClO4/c11-7-1-3-8(4-2-7)15-10(14)6-5-9(12)13/h1-6H,(H,12,13)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by PDSP Ki Database									J Pharmacol Exp Ther 302: 328-36 (2002) Article DOI: 10.1124/jpet.302.1.328 BindingDB Entry DOI: 10.7270/Q2JQ0ZK1
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM81466 (CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine) Show SMILES OC(=O)C=CC(=O)Oc1ccc(Cl)cc1 |w:4.4| Show InChI InChI=1S/C10H7ClO4/c11-7-1-3-8(4-2-7)15-10(14)6-5-9(12)13/h1-6H,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	211	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by PDSP Ki Database									J Pharmacol Exp Ther 302: 328-36 (2002) Article DOI: 10.1124/jpet.302.1.328 BindingDB Entry DOI: 10.7270/Q2JQ0ZK1
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM81466 (CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine) Show SMILES OC(=O)C=CC(=O)Oc1ccc(Cl)cc1 |w:4.4| Show InChI InChI=1S/C10H7ClO4/c11-7-1-3-8(4-2-7)15-10(14)6-5-9(12)13/h1-6H,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	361	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by PDSP Ki Database									J Pharmacol Exp Ther 302: 328-36 (2002) Article DOI: 10.1124/jpet.302.1.328 BindingDB Entry DOI: 10.7270/Q2JQ0ZK1
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM81466 (CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine) Show SMILES OC(=O)C=CC(=O)Oc1ccc(Cl)cc1 |w:4.4| Show InChI InChI=1S/C10H7ClO4/c11-7-1-3-8(4-2-7)15-10(14)6-5-9(12)13/h1-6H,(H,12,13)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 75: 6290-4 (1978) Article DOI: 10.1073/pnas.75.12.6290 BindingDB Entry DOI: 10.7270/Q2FN14P6
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM81466 (CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine) Show SMILES OC(=O)C=CC(=O)Oc1ccc(Cl)cc1 |w:4.4| Show InChI InChI=1S/C10H7ClO4/c11-7-1-3-8(4-2-7)15-10(14)6-5-9(12)13/h1-6H,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation Curated by PDSP Ki Database									Brain Res 304: 1-7 (1984) Article DOI: 10.1016/0006-8993(84)90856-4 BindingDB Entry DOI: 10.7270/Q21N7ZMS
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM81466 (CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine) Show SMILES OC(=O)C=CC(=O)Oc1ccc(Cl)cc1 |w:4.4| Show InChI InChI=1S/C10H7ClO4/c11-7-1-3-8(4-2-7)15-10(14)6-5-9(12)13/h1-6H,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 71: 1725-9 (1974) Article DOI: 10.1073/pnas.71.5.1725 BindingDB Entry DOI: 10.7270/Q2PC30WD
					More data for this Ligand-Target Pair