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BDBM81470 CAS_14677::Methdilazine::NSC_14677::US9504692, 3943

SMILES: CN1CCC(CN2c3ccccc3Sc3ccccc23)C1

InChI Key: InChIKey=HTMIBDQKFHUPSX-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 81470   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GST-MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM81470
PNG
(CAS_14677 | Methdilazine | NSC_14677 | US9504692, ...)
Show SMILES CN1CCC(CN2c3ccccc3Sc3ccccc23)C1
Show InChI InChI=1S/C18H20N2S/c1-19-11-10-14(12-19)13-20-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)20/h2-9,14H,10-13H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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antibodypedia
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DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 6.25E+3n/an/an/an/an/an/a



HELMHOLTZ ZENTRUM MUNCHEN, DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH)

US Patent


Assay Description
To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM81470
PNG
(CAS_14677 | Methdilazine | NSC_14677 | US9504692, ...)
Show SMILES CN1CCC(CN2c3ccccc3Sc3ccccc23)C1
Show InChI InChI=1S/C18H20N2S/c1-19-11-10-14(12-19)13-20-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)20/h2-9,14H,10-13H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

PubMed
2.30n/an/an/an/an/an/an/an/a



TBA

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair