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SMILES: N=C1NC(=O)\C(S1)=C/c1c[nH]c(=O)c(c1)-c1ccc(nc1)N1CCNCC1

InChI Key: InChIKey=BRYJBRLRAMEQPS-RIYZIHGNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 81551   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Homeodomain-interacting protein kinase 2


(Homo sapiens (Human))		BDBM81551
PNG
(Furan thiazolidinediones, A64)
Show SMILES N=C1NC(=O)\C(S1)=C/c1c[nH]c(=O)c(c1)-c1ccc(nc1)N1CCNCC1
Show InChI InChI=1S/C18H18N6O2S/c19-18-23-17(26)14(27-18)8-11-7-13(16(25)22-9-11)12-1-2-15(21-10-12)24-5-3-20-4-6-24/h1-2,7-10,20H,3-6H2,(H,22,25)(H2,19,23,26)/b14-8+
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n/an/a 74 9.5n/an/an/an/an/a



Harvard Medical School



Assay Description
In vitro biochemical assays were performed in parallel to determine the most potent tool compound.

Chem Biol 18: 868-79 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.010
BindingDB Entry DOI: 10.7270/Q2HD7T57
More data for this
Ligand-Target Pair