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BDBM81565 Magreth-17a

SMILES: CCCOc1ccc(CC=C)cc1-c1ccc(O)c(CC=C)c1

InChI Key: InChIKey=CPNPKRREQMIDHL-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 81565   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM81565
PNG
(Magreth-17a)
Show SMILES CCCOc1ccc(CC=C)cc1-c1ccc(O)c(CC=C)c1
Show InChI InChI=1S/C21H24O2/c1-4-7-16-9-12-21(23-13-6-3)19(14-16)17-10-11-20(22)18(15-17)8-5-2/h4-5,9-12,14-15,22H,1-2,6-8,13H2,3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
57n/an/an/an/an/an/an/an/a



University of Bern



Assay Description
Binding assay with hCB1 and hCB2 receptors.


Chem Biol 18: 1053-64 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.012
BindingDB Entry DOI: 10.7270/Q27W69PQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM81565
PNG
(Magreth-17a)
Show SMILES CCCOc1ccc(CC=C)cc1-c1ccc(O)c(CC=C)c1
Show InChI InChI=1S/C21H24O2/c1-4-7-16-9-12-21(23-13-6-3)19(14-16)17-10-11-20(22)18(15-17)8-5-2/h4-5,9-12,14-15,22H,1-2,6-8,13H2,3H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>5.00E+3n/an/an/an/an/an/an/an/a



University of Bern



Assay Description
Binding assay with hCB1 and hCB2 receptors.


Chem Biol 18: 1053-64 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.012
BindingDB Entry DOI: 10.7270/Q27W69PQ
More data for this
Ligand-Target Pair
GABA-A receptor; GABA-A site (alpha1/beta2 interface)


(Homo sapiens (Human))
BDBM81565
PNG
(Magreth-17a)
Show SMILES CCCOc1ccc(CC=C)cc1-c1ccc(O)c(CC=C)c1
Show InChI InChI=1S/C21H24O2/c1-4-7-16-9-12-21(23-13-6-3)19(14-16)17-10-11-20(22)18(15-17)8-5-2/h4-5,9-12,14-15,22H,1-2,6-8,13H2,3H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.48E+4n/an/an/an/a



University of Vienna

Curated by ChEMBL


Assay Description
Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding pot...


J Med Chem 54: 5349-61 (2011)


Article DOI: 10.1021/jm200186n
BindingDB Entry DOI: 10.7270/Q2QR4XGP
More data for this
Ligand-Target Pair