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BDBM81635 BZD Scaffold, 5

SMILES: [O-]C(=O)C(N1C(c2ccc(Cl)cc2)C(=O)Nc2ccc(I)cc2C1=O)c1ccccc1

InChI Key: InChIKey=MEFYLJNDZCLFKZ-UHFFFAOYSA-M

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 81635   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
p53 binding protein


(Homo sapiens (Human))		BDBM81635
PNG
(BZD Scaffold, 5)
Show SMILES [O-]C(=O)C(N1C(c2ccc(Cl)cc2)C(=O)Nc2ccc(I)cc2C1=O)c1ccccc1
Show InChI InChI=1S/C23H16ClIN2O4/c24-15-8-6-14(7-9-15)19-21(28)26-18-11-10-16(25)12-17(18)22(29)27(19)20(23(30)31)13-4-2-1-3-5-13/h1-12,19-20H,(H,26,28)(H,30,31)/p-1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development



Assay Description
Binding assay using 1,4-benzodiazepine-2,5-dione (BZD) scaffold and HDM2-p53 protein.

Chem Biol Drug Des 67: 201-5 (2006)


Article DOI: 10.1111/j.1747-0285.2006.00365.x
BindingDB Entry DOI: 10.7270/Q2BP018M
More data for this
Ligand-Target Pair