BDBM81692 4-Substituted Pyrrolidine Ring, 14
SMILES: NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)[C@H]2CC(O)CN2C(=O)Nc2ccc(Cl)cc2)c(F)c1
InChI Key: InChIKey=FOTQXLYFKKVZMB-FBLFFUNLSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM81692 (4-Substituted Pyrrolidine Ring, 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development, | Assay Description FXa inhibition were determined by using an inhibition assay. | Chem Biol Drug Des 69: 444-50 (2007) Article DOI: 10.1111/j.1747-0285.2007.00520.x BindingDB Entry DOI: 10.7270/Q2PZ5799 | |||||||||||
More data for this Ligand-Target Pair |