BindingDB PrimarySearch

BDBM81772 ARC-239::CAS_122211::NSC_122211

SMILES: COc1ccccc1N1CCN(CCC2C(=O)c3ccccc3C(C)(C)C2=O)CC1

InChI Key: InChIKey=OSEADGVOKYGIER-UHFFFAOYSA-N

Data: 24 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 81772
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
adrenergic Alpha2 (RAT)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (NEONATAL RAT)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (NEONATAL RAT)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	2.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	2.67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	3.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (OPOSSUM)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	12.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
ADRA2C (OK)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
ADRA2C (OK)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	19.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 1558-65 (1994) BindingDB Entry DOI: 10.7270/Q2G73C76
University of Michigan Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	31.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 1558-65 (1994) BindingDB Entry DOI: 10.7270/Q2G73C76
University of Michigan Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (OPOSSUM)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	46.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
ADRA2C (OPOSSUM)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (BOVINE)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	171	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	171	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	219	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (BOVINE)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	324	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (BOVINE)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	352	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 735-40 (1994) BindingDB Entry DOI: 10.7270/Q2VD6X0Z
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (PIG)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	Reactome pathway KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	365	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 735-40 (1994) BindingDB Entry DOI: 10.7270/Q2VD6X0Z
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	373	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo SmithKline Pharmaceuticals Curated by PDSP K_i Database									J Pharmacol Exp Ther 298: 219-25 (2001) BindingDB Entry DOI: 10.7270/Q2MS3R9D
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus (rat))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	484	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo SmithKline Pharmaceuticals Curated by PDSP K_i Database									J Pharmacol Exp Ther 298: 219-25 (2001) BindingDB Entry DOI: 10.7270/Q2MS3R9D
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus (rat))	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	749	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 735-40 (1994) BindingDB Entry DOI: 10.7270/Q2VD6X0Z
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RABBIT)	BDBM81772 (ARC-239 \| CAS_122211 \| NSC_122211) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo SmithKline Pharmaceuticals Curated by PDSP K_i Database									J Pharmacol Exp Ther 298: 219-25 (2001) BindingDB Entry DOI: 10.7270/Q2MS3R9D
					More data for this Ligand-Target Pair