BindingDB PrimarySearch

BDBM81773 BAM 1303::BAM-1303::CAS_115219-10-8

SMILES: CN1C[C@H](Cn2ccnc2-c2ccccc2)C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13

InChI Key: InChIKey=VKABNRMTNPWHBD-ZWDAVXSWSA-N

Data: 24 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 81773
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
adrenergic Alpha2 (OPOSSUM)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
ADRA2C (OK)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
ADRA2C (OK)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (OPOSSUM)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (PIG)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	Reactome pathway KEGG GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 735-40 (1994) BindingDB Entry DOI: 10.7270/Q2VD6X0Z
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	1.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	1.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	5.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	6.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (NEONATAL RAT)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	6.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									Mol Pharmacol 42: 1-5 (1992) BindingDB Entry DOI: 10.7270/Q2WH2NGR
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	18.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo SmithKline Pharmaceuticals Curated by PDSP K_i Database									J Pharmacol Exp Ther 298: 219-25 (2001) BindingDB Entry DOI: 10.7270/Q2MS3R9D
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (NEONATAL RAT)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus (rat))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 735-40 (1994) BindingDB Entry DOI: 10.7270/Q2VD6X0Z
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RABBIT)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo SmithKline Pharmaceuticals Curated by PDSP K_i Database									J Pharmacol Exp Ther 298: 219-25 (2001) BindingDB Entry DOI: 10.7270/Q2MS3R9D
					More data for this Ligand-Target Pair
adrenergic Alpha2 (BOVINE)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	KEGG GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	53.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RABBIT)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	95.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo SmithKline Pharmaceuticals Curated by PDSP K_i Database									J Pharmacol Exp Ther 298: 219-25 (2001) BindingDB Entry DOI: 10.7270/Q2MS3R9D
					More data for this Ligand-Target Pair
adrenergic Alpha2 (BOVINE)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	KEGG GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	149	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 735-40 (1994) BindingDB Entry DOI: 10.7270/Q2VD6X0Z
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (BOVINE)	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	KEGG GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1362-7 (1994) BindingDB Entry DOI: 10.7270/Q24X569K
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Rattus norvegicus (rat))	BDBM81773 (BAM 1303 \| BAM-1303 \| CAS_115219-10-8) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	313	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo SmithKline Pharmaceuticals Curated by PDSP K_i Database									J Pharmacol Exp Ther 298: 219-25 (2001) BindingDB Entry DOI: 10.7270/Q2MS3R9D
					More data for this Ligand-Target Pair