BDBM81777 CAS_132-66-1::NPA::NPA,(+)::NPA,(-)::NSC_8594

SMILES: OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12

InChI Key: InChIKey=JXTHEWSKYLZVJC-UHFFFAOYSA-N

Data: 18 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 81777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DRD2 (CANINE)	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP Ki Database									Nature 350: 610-4 (1991) Article DOI: 10.1038/350610a0 BindingDB Entry DOI: 10.7270/Q24T6GVD
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP Ki Database									J Pharmacol Exp Ther 264: 1002-11 (1993) BindingDB Entry DOI: 10.7270/Q2T1525C
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP Ki Database									Eur J Pharmacol 233: 173-4 (1993) Article DOI: 10.1016/0014-2999(93)90365-o BindingDB Entry DOI: 10.7270/Q25D8QBH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mus musculus (Mouse))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVO Industri A/S Curated by PDSP Ki Database									Eur J Pharmacol 146: 113-20 (1988) Article DOI: 10.1016/0014-2999(88)90492-x BindingDB Entry DOI: 10.7270/Q21R6P1H
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by PDSP Ki Database									J Pharmacol Exp Ther 262: 929-35 (1992) BindingDB Entry DOI: 10.7270/Q2RR1WQK
					More data for this Ligand-Target Pair
DRD2 (CANINE)	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP Ki Database									Nature 350: 610-4 (1991) Article DOI: 10.1038/350610a0 BindingDB Entry DOI: 10.7270/Q24T6GVD
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mus musculus (Mouse))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	7.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Service Curated by PDSP Ki Database									Mol Pharmacol 39: 570-8 (1991) BindingDB Entry DOI: 10.7270/Q26M359X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP Ki Database									Eur J Pharmacol 233: 173-4 (1993) Article DOI: 10.1016/0014-2999(93)90365-o BindingDB Entry DOI: 10.7270/Q25D8QBH
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Maryland Psychiatric Research Center Curated by PDSP Ki Database									Eur J Pharmacol 236: 483-6 (1993) Article DOI: 10.1016/0014-2999(93)90488-4 BindingDB Entry DOI: 10.7270/Q25Q4TKG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	291	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Maryland Psychiatric Research Center Curated by PDSP Ki Database									Eur J Pharmacol 236: 483-6 (1993) Article DOI: 10.1016/0014-2999(93)90488-4 BindingDB Entry DOI: 10.7270/Q25Q4TKG
					More data for this Ligand-Target Pair
Dopamine D1 receptor (Mus musculus (Mouse))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVO Industri A/S Curated by PDSP Ki Database									Eur J Pharmacol 146: 113-20 (1988) Article DOI: 10.1016/0014-2999(88)90492-x BindingDB Entry DOI: 10.7270/Q21R6P1H
					More data for this Ligand-Target Pair
Dopamine D1B (RAT)	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 88: 7491-5 (1991) Article DOI: 10.1073/pnas.88.17.7491 BindingDB Entry DOI: 10.7270/Q2DB80B9
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP Ki Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 88: 7491-5 (1991) Article DOI: 10.1073/pnas.88.17.7491 BindingDB Entry DOI: 10.7270/Q2DB80B9
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP Ki Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill, Chapel Hill Curated by PDSP Ki Database									J Pharmacol Exp Ther 301: 1179-89 (2002) Article DOI: 10.1124/jpet.301.3.1179 BindingDB Entry DOI: 10.7270/Q2QF8RFK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill, Chapel Hill Curated by PDSP Ki Database									J Pharmacol Exp Ther 301: 1179-89 (2002) Article DOI: 10.1124/jpet.301.3.1179 BindingDB Entry DOI: 10.7270/Q2QF8RFK
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM81777 (CAS_132-66-1 | NPA | NPA,(+) | NPA,(-) | NSC_8594) Show SMILES OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	3.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McLean Hospital Curated by PDSP Ki Database									J Med Chem 51: 983-7 (2008) Article DOI: 10.1021/jm701045j BindingDB Entry DOI: 10.7270/Q2V69H59
					More data for this Ligand-Target Pair