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BDBM81846 Bipiperidinyl carboxylic acid amide, 18

SMILES: Cc1cccc(n1)N1CCN(CC1)C(=O)C1CCCN(C1)C1CCN(CC1)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=SZCHIWACHPAATA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 81846   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 4 (CCR4)


(Homo sapiens (Human))		BDBM81846
PNG
(Bipiperidinyl carboxylic acid amide, 18)
Show SMILES Cc1cccc(n1)N1CCN(CC1)C(=O)C1CCCN(C1)C1CCN(CC1)C(=O)Nc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C29H37F3N6O2/c1-21-4-2-6-26(33-21)35-16-18-36(19-17-35)27(39)22-5-3-13-38(20-22)25-11-14-37(15-12-25)28(40)34-24-9-7-23(8-10-24)29(30,31)32/h2,4,6-10,22,25H,3,5,11-20H2,1H3,(H,34,40)
UniProtKB/SwissProt
UniProtKB/TrEMBL

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Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Pfizer



Assay Description
Cell-based assay for CCR4 was developed to screen small-molecule compound library using a Fluorometric Imaging Plate Reader (FlIPR) assay to identify...

Chem Biol Drug Des 70: 268-72 (2007)


Article DOI: 10.1111/j.1747-0285.2007.00551.x
BindingDB Entry DOI: 10.7270/Q2K35S44
More data for this
Ligand-Target Pair