BDBM81896 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,11-[2-[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-, (+)-::AF-DX 250::CAS_121029-35-4

SMILES: CCN(CC)CC1CCCCN1CC(=O)N1c2ccccc2NC(=O)c2ccccc12

InChI Key: InChIKey=RLUNJKJUFRFYJM-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 81896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM81896 (6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,11-[2-[2-...) Show SMILES CCN(CC)CC1CCCCN1CC(=O)N1c2ccccc2NC(=O)c2ccccc12 Show InChI InChI=1S/C25H32N4O2/c1-3-27(4-2)17-19-11-9-10-16-28(19)18-24(30)29-22-14-7-5-12-20(22)25(31)26-21-13-6-8-15-23(21)29/h5-8,12-15,19H,3-4,9-11,16-18H2,1-2H3,(H,26,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PubMed	55.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by PDSP Ki Database									J Pharmacol Exp Ther 256: 727-33 (1991) BindingDB Entry DOI: 10.7270/Q2VD6WZ3
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM81896 (6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,11-[2-[2-...) Show SMILES CCN(CC)CC1CCCCN1CC(=O)N1c2ccccc2NC(=O)c2ccccc12 Show InChI InChI=1S/C25H32N4O2/c1-3-27(4-2)17-19-11-9-10-16-28(19)18-24(30)29-22-14-7-5-12-20(22)25(31)26-21-13-6-8-15-23(21)29/h5-8,12-15,19H,3-4,9-11,16-18H2,1-2H3,(H,26,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by PDSP Ki Database									J Pharmacol Exp Ther 256: 727-33 (1991) BindingDB Entry DOI: 10.7270/Q2VD6WZ3
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM81896 (6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,11-[2-[2-...) Show SMILES CCN(CC)CC1CCCCN1CC(=O)N1c2ccccc2NC(=O)c2ccccc12 Show InChI InChI=1S/C25H32N4O2/c1-3-27(4-2)17-19-11-9-10-16-28(19)18-24(30)29-22-14-7-5-12-20(22)25(31)26-21-13-6-8-15-23(21)29/h5-8,12-15,19H,3-4,9-11,16-18H2,1-2H3,(H,26,31)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PubMed	427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by PDSP Ki Database									J Pharmacol Exp Ther 256: 727-33 (1991) BindingDB Entry DOI: 10.7270/Q2VD6WZ3
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM81896 (6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,11-[2-[2-...) Show SMILES CCN(CC)CC1CCCCN1CC(=O)N1c2ccccc2NC(=O)c2ccccc12 Show InChI InChI=1S/C25H32N4O2/c1-3-27(4-2)17-19-11-9-10-16-28(19)18-24(30)29-22-14-7-5-12-20(22)25(31)26-21-13-6-8-15-23(21)29/h5-8,12-15,19H,3-4,9-11,16-18H2,1-2H3,(H,26,31)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PubMed	692	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by PDSP Ki Database									J Pharmacol Exp Ther 256: 727-33 (1991) BindingDB Entry DOI: 10.7270/Q2VD6WZ3
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM81896 (6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,11-[2-[2-...) Show SMILES CCN(CC)CC1CCCCN1CC(=O)N1c2ccccc2NC(=O)c2ccccc12 Show InChI InChI=1S/C25H32N4O2/c1-3-27(4-2)17-19-11-9-10-16-28(19)18-24(30)29-22-14-7-5-12-20(22)25(31)26-21-13-6-8-15-23(21)29/h5-8,12-15,19H,3-4,9-11,16-18H2,1-2H3,(H,26,31)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PubMed	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by PDSP Ki Database									J Pharmacol Exp Ther 256: 727-33 (1991) BindingDB Entry DOI: 10.7270/Q2VD6WZ3
					More data for this Ligand-Target Pair