BindingDB PrimarySearch

BDBM81972 (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROBROMIDE::Alpha-Methylhistamine-S::CAS_75614-93-6

SMILES: C[C@H](N)Cc1cnc[nH]1

InChI Key: InChIKey=XNQIOISZPFVUFG-YFKPBYRVSA-N

Data: 7 KI 3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 81972
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Platelet activating factor receptor (Homo sapiens (Human))	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	PDB Reactome pathway KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparation				J Med Chem 35: 3474-82 (1992) BindingDB Entry DOI: 10.7270/Q2445N3B
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
HRH3 (RAT)	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Unité 109 Curated by PDSP K_i Database									Invest Radiol -2 (1988) Article DOI: 10.1097/00004424-198809001-00017 BindingDB Entry DOI: 10.7270/Q22R3Q5W
Unité 109 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Platelet activating factor receptor (Homo sapiens (Human))	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	PDB Reactome pathway KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article	14.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-C18 PAF binding to human platelet membrane Platelet activating factor receptor was determined				Bioorg Med Chem Lett 2: 181-184 (1992) Article DOI: 10.1016/S0960-894X(01)80446-7 BindingDB Entry DOI: 10.7270/Q24X588Z
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
HRH3 (RAT)	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
U. 109 Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 452-9 (1994) BindingDB Entry DOI: 10.7270/Q23X8556
U. 109 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HRH3 (GUINEA PIG)	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Unité 109 Curated by PDSP K_i Database									Invest Radiol -2 (1988) Article DOI: 10.1097/00004424-198809001-00017 BindingDB Entry DOI: 10.7270/Q22R3Q5W
Unité 109 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HRH3 (RAT)	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
U. 109 Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 452-9 (1994) BindingDB Entry DOI: 10.7270/Q23X8556
U. 109 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HRH3 (RAT)	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
U. 109 Curated by PDSP K_i Database									J Pharmacol Exp Ther 271: 452-9 (1994) BindingDB Entry DOI: 10.7270/Q23X8556
U. 109 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Platelet activating factor receptor (Cavia porcellus)	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris 7 Curated by ChEMBL					Assay Description Inhibition of PAF-induced rabbit platelet aggregation				J Med Chem 36: 990-1000 (1993) BindingDB Entry DOI: 10.7270/Q2MC90NX
Universit£ Paris 7 Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet activating factor receptor (Homo sapiens (Human))	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	PDB Reactome pathway KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]PAF receptor binding to washed human platelet membranes				Bioorg Med Chem Lett 3: 1493-1498 (1993) Article DOI: 10.1016/S0960-894X(00)80005-0 BindingDB Entry DOI: 10.7270/Q2H132H9
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet activating factor receptor (Homo sapiens (Human))	BDBM81972 ((S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIH...) Show SMILES C[C@H](N)Cc1cnc[nH]1 \|r\| Show InChI	PDB Reactome pathway KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]PAF receptor binding to washed human platelet membranes determined in vitro				Bioorg Med Chem Lett 3: 1499-1504 (1993) Article DOI: 10.1016/S0960-894X(00)80006-2 BindingDB Entry DOI: 10.7270/Q2CC115V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair