BindingDB PrimarySearch

BDBM81979 CAS_5051-62-7::CAS_65636::Fluprofylline::Guanabenz::NSC_3517::NSC_65636

SMILES: [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1c(Cl)cccc1Cl

InChI Key: InChIKey=WDZVGELJXXEGPV-UHFFFAOYSA-N

Data: 10 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 81979
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
adrenergic Alpha2 (RAT)	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP K_i Database									J Pharmacol Exp Ther 241: 1092-8 (1987) BindingDB Entry DOI: 10.7270/Q2F18X7B
University of California Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	21.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Biochem Pharmacol 55: 1035-43 (1998) Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	28.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Oregon Health Sciences University Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 83: 8784-8 (1986) Article DOI: 10.1073/pnas.83.22.8784 BindingDB Entry DOI: 10.7270/Q2V122XD
					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	PubMed	36.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP K_i Database									J Pharmacol Exp Ther 241: 1092-8 (1987) BindingDB Entry DOI: 10.7270/Q2F18X7B
University of California Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (PIG)	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	Reactome pathway KEGG GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	PubMed	57.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by PDSP K_i Database									J Pharmacol Exp Ther 294: 539-47 (2000) BindingDB Entry DOI: 10.7270/Q2TM78NR
University of Michigan Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Oregon Health Sciences University Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 83: 8784-8 (1986) Article DOI: 10.1073/pnas.83.22.8784 BindingDB Entry DOI: 10.7270/Q2V122XD
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Biochem Pharmacol 55: 1035-43 (1998) Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	447	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Biochem Pharmacol 55: 1035-43 (1998) Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									J Pharm Pharmacol 38: 374-9 (1986) Article DOI: 10.1111/j.2042-7158.1986.tb04590.x BindingDB Entry DOI: 10.7270/Q2JS9NXW
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM81979 (CAS_5051-62-7 \| CAS_65636 \| Fluprofylline \| Guanab...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Oregon Health Sciences University Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 83: 8784-8 (1986) Article DOI: 10.1073/pnas.83.22.8784 BindingDB Entry DOI: 10.7270/Q2V122XD
					More data for this Ligand-Target Pair