BDBM82185 Sulfosalazine, 3
SMILES: OC(=O)c1ccc(cc1O)\N=N\c1ccc(cc1)S(=O)(=O)Nc1ccccn1
InChI Key: InChIKey=GTTWYCNVHRAJHM-QZQOTICOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM82185 (Sulfosalazine, 3) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.70E+5 | n/a | 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi... | Chem Biol Drug Des 76: 552-8 (2010) Article DOI: 10.1111/j.1747-0285.2010.01036.x BindingDB Entry DOI: 10.7270/Q2Q52N3T | |||||||||||
More data for this Ligand-Target Pair |