BDBM84143 3-(2,3-dimethoxyphenyl)-2-(4-methylphenyl)sulfonyl-5-phenyl-3,4-dihydropyrazole::5-(2,3-dimethoxyphenyl)-3-phenyl-1-tosyl-2-pyrazoline::MLS000680475::SMR000324612::cid_5052359
SMILES: COc1cccc(C2CC(=NN2S(=O)(=O)c2ccc(C)cc2)c2ccccc2)c1OC
InChI Key: InChIKey=QQPYSSRVXYDNEL-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Candida albicans strain ATCC 10261 multidrug efflux pump (MDR1) gene, MDR1-A allele, complete cds (Candida albicans) | BDBM84143 (3-(2,3-dimethoxyphenyl)-2-(4-methylphenyl)sulfonyl...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 9.58E+3 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description UNMCMD Assay Overview: Assay Support: 1 R03 MH087406-01A1 Project Title: Identification of broad-spectrum antifungal efflux pump inhibitors ... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q20V8B9F | |||||||||||
More data for this Ligand-Target Pair |