BDBM8415 (5Z)-5-{[5-(4-chlorophenyl)furan-2-yl]methylidene}-3-(furan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one::Rhodanine-furan analogue 2

SMILES: Clc1ccc(cc1)-c1ccc(\C=C2/SC(=S)N(Cc3ccco3)C2=O)o1

InChI Key: InChIKey=FAVIEKHNXCLRPT-YVLHZVERSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Anthrax Lethal Factor (LF) (Bacillus anthracis)	BDBM8415 ((5Z)-5-{[5-(4-chlorophenyl)furan-2-yl]methylidene}...) Show SMILES Clc1ccc(cc1)-c1ccc(\C=C2/SC(=S)N(Cc3ccco3)C2=O)o1 Show InChI InChI=1S/C19H12ClNO3S2/c20-13-5-3-12(4-6-13)16-8-7-14(24-16)10-17-18(22)21(19(25)26-17)11-15-2-1-9-23-15/h1-10H,11H2/b17-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	7.4	22
Burnham Institute for Medical Research					Assay Description Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...				Proc Natl Acad Sci U S A 102: 9499-504 (2005) Article DOI: 10.1073/pnas.0502733102 BindingDB Entry DOI: 10.7270/Q2TM78BQ
					More data for this Ligand-Target Pair