Found 11 hits for monomerid = 85066 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melatonin
(RABBIT) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 355: 365-75 (1997)
Article DOI: 10.1007/pl00004956 BindingDB Entry DOI: 10.7270/Q2416VKF |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 355: 365-75 (1997)
Article DOI: 10.1007/pl00004956 BindingDB Entry DOI: 10.7270/Q2416VKF |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nantong University
Curated by ChEMBL
| Assay Description Displacement of 2-[1251]-iodomelatonin from human MT2 receptor expressed in COS7 cells incubated for 1.5 hrs by gamma counting method |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111847 |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The German University in Cairo
Curated by ChEMBL
| Assay Description Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in African green monkey COS7 cells |
J Med Chem 57: 3161-85 (2014)
Article DOI: 10.1021/jm401343c BindingDB Entry DOI: 10.7270/Q218381K |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 355: 365-75 (1997)
Article DOI: 10.1007/pl00004956 BindingDB Entry DOI: 10.7270/Q2416VKF |
More data for this Ligand-Target Pair | |
Melatonin
(RABBIT) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 355: 365-75 (1997)
Article DOI: 10.1007/pl00004956 BindingDB Entry DOI: 10.7270/Q2416VKF |
More data for this Ligand-Target Pair | |
Melatonin
(RABBIT) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 355: 365-75 (1997)
Article DOI: 10.1007/pl00004956 BindingDB Entry DOI: 10.7270/Q2416VKF |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 32.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 355: 365-75 (1997)
Article DOI: 10.1007/pl00004956 BindingDB Entry DOI: 10.7270/Q2416VKF |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 32.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 355: 365-75 (1997)
Article DOI: 10.1007/pl00004956 BindingDB Entry DOI: 10.7270/Q2416VKF |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nantong University
Curated by ChEMBL
| Assay Description Displacement of 2-[1251]-iodomelatonin from human MT1 receptor expressed in COS7 cells incubated for 1.5 hrs by gamma counting method |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111847 |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM85066
(Luzindole,5-Methoxy)Show InChI InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The German University in Cairo
Curated by ChEMBL
| Assay Description Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cells |
J Med Chem 57: 3161-85 (2014)
Article DOI: 10.1021/jm401343c BindingDB Entry DOI: 10.7270/Q218381K |
More data for this Ligand-Target Pair | |