BDBM85077 3-Phosphono-D,L-2-aminopropionic acid, 7::CAS_23052-80-4::L-AP3::NSC_3857

SMILES: NC(CP(O)(O)=O)C(O)=O

InChI Key: InChIKey=LBTABPSJONFLPO-UHFFFAOYSA-N

Data: 8 KI

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 85077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM85077 (3-Phosphono-D,L-2-aminopropionic acid, 7 | CAS_230...) Show SMILES NC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	263	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									J Neurochem 71: 2558-64 (1998) Article DOI: 10.1046/j.1471-4159.1998.71062558.x BindingDB Entry DOI: 10.7270/Q25D8QCZ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM85077 (3-Phosphono-D,L-2-aminopropionic acid, 7 | CAS_230...) Show SMILES NC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP Ki Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM85077 (3-Phosphono-D,L-2-aminopropionic acid, 7 | CAS_230...) Show SMILES NC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP Ki Database									Mol Pharmacol 53: 228-33 (1998) BindingDB Entry DOI: 10.7270/Q2MP51T5
					More data for this Ligand-Target Pair
GRIA3 (RAT)	BDBM85077 (3-Phosphono-D,L-2-aminopropionic acid, 7 | CAS_230...) Show SMILES NC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP Ki Database									J Pharmacol Exp Ther 298: 453-60 (2001) Article DOI: 10.1016/j.bioorg.2016.02.004 BindingDB Entry DOI: 10.7270/Q2V986M2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM85077 (3-Phosphono-D,L-2-aminopropionic acid, 7 | CAS_230...) Show SMILES NC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Curated by PDSP Ki Database									J Neurochem 75: 2590-601 (2000) Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM85077 (3-Phosphono-D,L-2-aminopropionic acid, 7 | CAS_230...) Show SMILES NC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP Ki Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM85077 (3-Phosphono-D,L-2-aminopropionic acid, 7 | CAS_230...) Show SMILES NC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Curated by PDSP Ki Database									J Neurochem 75: 2590-601 (2000) Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ
					More data for this Ligand-Target Pair
Glycosylasparaginase (GA) (Homo sapiens (Human))	BDBM85077 (3-Phosphono-D,L-2-aminopropionic acid, 7 | CAS_230...) Show SMILES NC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)	MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	9.00E+5	-4.32	n/a	n/a	n/a	n/a	n/a	5.8	37
University of North Carolina					Assay Description Glycosylasparaginase activity was measured in citrate-phosphate buffer at pH 5.8 at 37 C. N-Acetyl-D-glucosamine released during the reaction was me...				J Enzym Inhib 16: 269-74 (2001) Article DOI: 10.1080/14756360109162375 BindingDB Entry DOI: 10.7270/Q2P55M2S
					More data for this Ligand-Target Pair