BindingDB PrimarySearch

BDBM85166 CAS_3292447::NSC_3292447::SB 216641

SMILES: COc1ccc(NC(=O)c2ccc(cc2)-c2ccc(cc2C)-c2noc(C)n2)cc1OCCN(C)C

InChI Key: InChIKey=JRNUKVFYILMMLX-UHFFFAOYSA-N

Data: 15 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 85166
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	25.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	31.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 2A receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM85166 (CAS_3292447 \| NSC_3292447 \| SB 216641) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 356: 312-20 (1997) Article DOI: 10.1007/pl00005056 BindingDB Entry DOI: 10.7270/Q2KW5DKB
					More data for this Ligand-Target Pair