BindingDB PrimarySearch

BDBM85213 Agmatine::CAS_306-60-5::CHEMBL58343::NSC_199::US8633208, Agmatine

SMILES: [#7]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7]

InChI Key: InChIKey=QYPPJABKJHAVHS-UHFFFAOYSA-N

Data: 6 KI 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 85213
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyamine oxidase 1 (Zea mays)	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method				J Med Chem 52: 4774-85 (2009) Article DOI: 10.1021/jm900371z BindingDB Entry DOI: 10.7270/Q2TB16W1
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by PDSP K_i Database									J Pharmacol Exp Ther 285: 170-7 (1998) BindingDB Entry DOI: 10.7270/Q27H1H4B
University of Bonn Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Ionotropic glutamate receptor subunit Delta2 (Xenopus)	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 740-8 (2003) Article DOI: 10.1124/jpet.102.045799 BindingDB Entry DOI: 10.7270/Q2N878C5
State University of New York Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by PDSP K_i Database									J Pharmacol Exp Ther 285: 170-7 (1998) BindingDB Entry DOI: 10.7270/Q27H1H4B
University of Bonn Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	8.60E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cologne Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of uptake of 0.1 uM MPP+ in OCT1-expressing 293 cells				J Pharmacol Exp Ther 304: 810-7 (2003) Article DOI: 10.1124/jpet.102.044404 BindingDB Entry DOI: 10.7270/Q2QC04RF
University of Cologne Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Homo sapiens (Human))	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	2.40E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cologne Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of uptake of 0.1 uM MPP+ in OCT1-expressing 293 cells				J Pharmacol Exp Ther 304: 810-7 (2003) Article DOI: 10.1124/jpet.102.044404 BindingDB Entry DOI: 10.7270/Q2QC04RF
University of Cologne Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gdansk University of Technology Curated by ChEMBL					Assay Description Inhibition of Wistar rat imidazoline I1 receptor				Bioorg Med Chem 19: 156-67 (2011) Article DOI: 10.1016/j.bmc.2010.11.039 BindingDB Entry DOI: 10.7270/Q2GH9J79
Gdansk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Wistar rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Rottapharm S.p.A US Patent					Assay Description Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...				US Patent US8633208 (2014) BindingDB Entry DOI: 10.7270/Q23J3BMD
Rottapharm S.p.A US Patent					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Rottapharm S.p.A US Patent					Assay Description Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...				US Patent US8633208 (2014) BindingDB Entry DOI: 10.7270/Q23J3BMD
Rottapharm S.p.A US Patent					More data for this Ligand-Target Pair
Deoxyhypusine synthase (Rattus norvegicus)	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.56E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Dental Research Curated by ChEMBL					Assay Description In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.				J Med Chem 38: 3053-61 (1995) BindingDB Entry DOI: 10.7270/Q2P55MJ2
National Institute of Dental Research Curated by ChEMBL					More data for this Ligand-Target Pair