BDBM85316 GlcN-6-P synthase inhibitor, 9 (racemic mixture)
SMILES: CCN(CC)P(=O)(CCC(N)C(=O)OC)OC
InChI Key: InChIKey=MCRXVXJEYHZWRL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glucosamine-6- Phosphate Synthase (Candida albicans) | BDBM85316 (GlcN-6-P synthase inhibitor, 9 (racemic mixture)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | 9.40E+5 | n/a | 3.60E+6 | n/a | n/a | n/a | n/a | 6.85 | n/a | |
Technical University of Gdansk | Assay Description Two assays of GlcN-6-P synthase activity were used 1)determination of GlcN-6_P formation by the modified Elson-Morgan procedure and 2) continuous qua... | Bioorg Chem 25: 283-296 (1997) BindingDB Entry DOI: 10.7270/Q2RB7351 | |||||||||||
More data for this Ligand-Target Pair |