BindingDB logo
myBDB logout

null

SMILES: OC(=O)c1ccnc(NC(=O)C(CS)Cc2ccccc2)c1

InChI Key: InChIKey=VKTGABDIOFSGEW-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 85429   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM85429
PNG
(NEP inhibitor, 6i)
Show SMILES OC(=O)c1ccnc(NC(=O)C(CS)Cc2ccccc2)c1
Show InChI InChI=1S/C16H16N2O3S/c19-15(13(10-22)8-11-4-2-1-3-5-11)18-14-9-12(16(20)21)6-7-17-14/h1-7,9,13,22H,8,10H2,(H,20,21)(H,17,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 3n/an/an/an/an/a25



R&D, Zambon Group Spa



Assay Description
Enzyme inhibition assay using neutrol endopeptiase EC 3.4.24.11 (NEP).

J Enzym Inhib 12: 155-60 (1997)


Article DOI: 10.3109/14756369709035816
BindingDB Entry DOI: 10.7270/Q2FQ9V4F
More data for this
Ligand-Target Pair