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SMILES: OC(=O)c1cc(NC(=O)C(CS)Cc2ccccc2)cs1

InChI Key: InChIKey=VCFGVPMALWRCTK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 85431   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM85431
PNG
(NEP inhibitor, 6k)
Show SMILES OC(=O)c1cc(NC(=O)C(CS)Cc2ccccc2)cs1
Show InChI InChI=1S/C15H15NO3S2/c17-14(16-12-7-13(15(18)19)21-9-12)11(8-20)6-10-4-2-1-3-5-10/h1-5,7,9,11,20H,6,8H2,(H,16,17)(H,18,19)
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Article
PubMed
n/an/a 2n/an/an/an/an/a25



R&D, Zambon Group Spa



Assay Description
Enzyme inhibition assay using neutrol endopeptiase EC 3.4.24.11 (NEP).

J Enzym Inhib 12: 155-60 (1997)


Article DOI: 10.3109/14756369709035816
BindingDB Entry DOI: 10.7270/Q2FQ9V4F
More data for this
Ligand-Target Pair