BDBM85448 Epoxy analogue, I(b)
SMILES: C[C@H]1O[C@H]1C[C@H](N)C(O)=O
InChI Key: InChIKey=QFOIPOGZSOITTR-WISUUJSJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-Adenosylmethionine Synthase (AdoMet) (Rattus norvegicus) | BDBM85448 (Epoxy analogue, I(b)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.10E+4 | -5.98 | 1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair |