BindingDB PrimarySearch

BDBM85511 CAS_74103-07-4::KETOROLAC::Ketorolac tris salt::Toradol

SMILES: OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1

InChI Key: InChIKey=OZWKMVRBQXNZKK-UHFFFAOYSA-N

Data: 9 KI 15 IC50 1 Kd 1 ITC

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 85511
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
St. Bartholomew's and the Royal London School of Medicine and Dentistry Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 96: 7563-8 (1999) Article DOI: 10.1073/pnas.96.13.7563 BindingDB Entry DOI: 10.7270/Q21G0JT4
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
St. Bartholomew's and the Royal London School of Medicine and Dentistry Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 96: 7563-8 (1999) Article DOI: 10.1073/pnas.96.13.7563 BindingDB Entry DOI: 10.7270/Q21G0JT4
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
St. Bartholomew's and the Royal London School of Medicine and Dentistry Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 96: 7563-8 (1999) Article DOI: 10.1073/pnas.96.13.7563 BindingDB Entry DOI: 10.7270/Q21G0JT4
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dallas Department of Veterans Affairs Medical Center Curated by PDSP K_i Database									Am J Med 104: 413-21 (1998) Article DOI: 10.1016/s0002-9343(98)00091-6 BindingDB Entry DOI: 10.7270/Q2F18X97
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dallas Department of Veterans Affairs Medical Center Curated by PDSP K_i Database									Am J Med 104: 413-21 (1998) Article DOI: 10.1016/s0002-9343(98)00091-6 BindingDB Entry DOI: 10.7270/Q2F18X97
					More data for this Ligand-Target Pair
Intestinal fatty acid-binding protein (hIFABP) (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	9.40E+3	-13.0	n/a	n/a	n/a	n/a	n/a	n/a	293.15
Monash University					Assay Description Briefly, steady-state fluorescence spectra of ANS binding was monitored by measuring the increase in fluorescence signal between 450?550 nm following...				ACS Chem Biol 9: 2526-34 (2014) Article DOI: 10.1021/cb5005178 BindingDB Entry DOI: 10.7270/Q2348J4C
Monash University					More data for this Ligand-Target Pair				3D Structure (crystal)
Liver fatty acid binding protein (rat L-FABP) (Rattus norvegicus (Rat))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP high binding affinity site expressed in Escherichia coli BL21 by co...				J Med Chem 51: 3755-64 (2008) Article DOI: 10.1021/jm701192w BindingDB Entry DOI: 10.7270/Q2KH0P7G
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Liver fatty acid binding protein (rat L-FABP) (Rattus norvegicus (Rat))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP low binding affinity site expressed in Escherichia coli BL21 by com...				J Med Chem 51: 3755-64 (2008) Article DOI: 10.1021/jm701192w BindingDB Entry DOI: 10.7270/Q2KH0P7G
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Serum albumin (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.00E+14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Molecular Discovery Ltd. Curated by ChEMBL					Assay Description Binding affinity towards human serum albumin				J Med Chem 48: 2469-79 (2005) Article DOI: 10.1021/jm049227l BindingDB Entry DOI: 10.7270/Q2125WDN
Molecular Discovery Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Rho GTPase Rac1/CDC42 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Inhibition of RAC1/CDC42 in human ovarian cancer cells				Eur J Med Chem 126: 270-276 (2017) BindingDB Entry DOI: 10.7270/Q2T72KP7
Kagoshima University Curated by ChEMBL					More data for this Ligand-Target Pair
PAK 1/CDC42 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Inhibition of PAK1 in human A549 cells using myelin basic protein as substrate preincubated for 24 hrs followed by PAK1 immunoprecipation and substra...				Eur J Med Chem 126: 270-276 (2017) BindingDB Entry DOI: 10.7270/Q2T72KP7
Kagoshima University Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 4 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Canalicular multispecific organic anion transporter 2 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Canalicular multispecific organic anion transporter 1 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E synthase/G/H synthase 2 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Kagoshima University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate measured after 2 to 5 mins				Eur J Med Chem 126: 270-276 (2017) BindingDB Entry DOI: 10.7270/Q2T72KP7
Kagoshima University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	n/a	n/a	6.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Faculdade de Ci�ncias e Tecnologia-UNL Curated by ChEMBL					Assay Description Instantaneous inhibition of human COX2 measured immediately after incubation of enzyme with compound				J Med Chem 54: 8555-62 (2011) Article DOI: 10.1021/jm201090k BindingDB Entry DOI: 10.7270/Q2W95B6H
Faculdade de Ci�ncias e Tecnologia-UNL Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Faculdade de Ci�ncias e Tecnologia-UNL Curated by ChEMBL					Assay Description Inhibition of human COX2 measured after pre-incubation of enzyme with compound				J Med Chem 54: 8555-62 (2011) Article DOI: 10.1021/jm201090k BindingDB Entry DOI: 10.7270/Q2W95B6H
Faculdade de Ci�ncias e Tecnologia-UNL Curated by ChEMBL					More data for this Ligand-Target Pair
Caspase-9 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	7.4	n/a
University of Colorado					Assay Description Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...				Cell Chem Biol 24: 281-292 (2017) Article DOI: 10.1016/j.chembiol.2017.02.003 BindingDB Entry DOI: 10.7270/Q2C53JQX
University of Colorado					More data for this Ligand-Target Pair
Caspase-5 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.4	n/a
University of Colorado					Assay Description Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...				Cell Chem Biol 24: 281-292 (2017) Article DOI: 10.1016/j.chembiol.2017.02.003 BindingDB Entry DOI: 10.7270/Q2C53JQX
University of Colorado					More data for this Ligand-Target Pair
Caspase-4 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	7.4	n/a
University of Colorado					Assay Description Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...				Cell Chem Biol 24: 281-292 (2017) Article DOI: 10.1016/j.chembiol.2017.02.003 BindingDB Entry DOI: 10.7270/Q2C53JQX
University of Colorado					More data for this Ligand-Target Pair
Caspase-3 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	7.4	n/a
University of Colorado					Assay Description Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...				Cell Chem Biol 24: 281-292 (2017) Article DOI: 10.1016/j.chembiol.2017.02.003 BindingDB Entry DOI: 10.7270/Q2C53JQX
University of Colorado					More data for this Ligand-Target Pair
Caspase-1 (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	7.4	n/a
University of Colorado					Assay Description Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...				Cell Chem Biol 24: 281-292 (2017) Article DOI: 10.1016/j.chembiol.2017.02.003 BindingDB Entry DOI: 10.7270/Q2C53JQX
University of Colorado					More data for this Ligand-Target Pair
Intestinal fatty acid-binding protein (hIFABP) (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	5.67E+4	n/a	n/a	n/a	8.0	37
Monash University					Assay Description ITC experiments were carried out using an iTC200 microcalorimeter (MicroCal) with coin shaped sample cell (200 μL) at 37 C with stirring at 1000...				ACS Chem Biol 9: 2526-34 (2014) Article DOI: 10.1021/cb5005178 BindingDB Entry DOI: 10.7270/Q2348J4C
Monash University					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin-H2 D-isomerase (Mus musculus)	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...) Show SMILES OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Research Group Curated by ChEMBL					Assay Description Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes				J Med Chem 34: 1099-110 (1991) BindingDB Entry DOI: 10.7270/Q24M955S
Sterling Research Group Curated by ChEMBL					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 85511
Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
Intestinal fatty acid-binding protein (hIFABP) (Homo sapiens (Human))	BDBM85511 (CAS_74103-07-4 \| KETOROLAC \| Ketorolac tris salt \|...)	GoogleScholar PDB	DrugBank KEGG PC cid PC sid PDB		-6.02	-6.09	0.0717	4.24	8	37
Monash University		GoogleScholar PDB	DrugBank KEGG PC cid PC sid PDB		ACS Chem Biol 9: 2526-34 (2014)