BDBM86012 Chalcone, 11
SMILES: Oc1ccc(Cl)cc1C(=O)\C=C\c1ccc(Cl)cc1
InChI Key: InChIKey=TTWITESQDJUURJ-XVNBXDOJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lipoxygenase (Homo sapiens (Human)) | BDBM86012 (Chalcone, 11) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 7.17E+4 | -5.65 | n/a | n/a | n/a | n/a | n/a | 8.0 | 25 |
Quaid-i-Azam University | Assay Description In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel... | J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin alpha chain (Ovis aries) | BDBM86012 (Chalcone, 11) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi... | Citation and Details Article DOI: 10.1007/s00044-010-9344-z BindingDB Entry DOI: 10.7270/Q2KW5JW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldose reductase (Rattus norvegicus) | BDBM86012 (Chalcone, 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Rattus norvegicus (rat) lens aldose reductase | Citation and Details Article DOI: 10.1007/s00044-012-0367-5 BindingDB Entry DOI: 10.7270/Q2XP77VN | |||||||||||
More data for this Ligand-Target Pair |