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BDBM86021 2,2,6-Trimethyl-3,4,5,6-tetrahydro-2H-pyrano[3,2-c]quinoline-5-one, 2

SMILES: Cn1c2ccccc2c2OC(C)(C)[C@@H](O)Cc2c1=O

InChI Key: InChIKey=DWGJDUGVGKBCGA-LBPRGKRZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 86021   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM86021
PNG
(2,2,6-Trimethyl-3,4,5,6-tetrahydro-2H-pyrano[3,2-c...)
Show SMILES Cn1c2ccccc2c2OC(C)(C)[C@@H](O)Cc2c1=O |r|
Show InChI InChI=1S/C15H17NO3/c1-15(2)12(17)8-10-13(19-15)9-6-4-5-7-11(9)16(3)14(10)18/h4-7,12,17H,8H2,1-3H3/t12-/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
9.00E+4 -5.61n/an/an/an/an/an/a30



University of Karachi



Assay Description
AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...


J Enzyme Inhib Med Chem 21: 703-10 (2006)


Article DOI: 10.1080/14756360600889708
BindingDB Entry DOI: 10.7270/Q26D5RJS
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Tetronarce californica (Pacific electric ray) (Tor...)
BDBM86021
PNG
(2,2,6-Trimethyl-3,4,5,6-tetrahydro-2H-pyrano[3,2-c...)
Show SMILES Cn1c2ccccc2c2OC(C)(C)[C@@H](O)Cc2c1=O |r|
Show InChI InChI=1S/C15H17NO3/c1-15(2)12(17)8-10-13(19-15)9-6-4-5-7-11(9)16(3)14(10)18/h4-7,12,17H,8H2,1-3H3/t12-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.10E+5 -5.49n/an/an/an/an/an/a30



University of Karachi



Assay Description
AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...


J Enzyme Inhib Med Chem 21: 703-10 (2006)


Article DOI: 10.1080/14756360600889708
BindingDB Entry DOI: 10.7270/Q26D5RJS
More data for this
Ligand-Target Pair