new BindingDB logo
myBDB logout

BDBM86032 trans-H2-PAT(-)::trans-PAT

SMILES: CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1

InChI Key: InChIKey=DXJUCAUQIHNOAF-SJLPKXTDSA-N

Data: 9 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 86032   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
0.580n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by PDSP Ki Database




J Pharmacol Exp Ther 302: 328-36 (2002)


Article DOI: 10.1124/jpet.302.1.328
BindingDB Entry DOI: 10.7270/Q2JQ0ZK1
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.15n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by PDSP Ki Database




J Pharmacol Exp Ther 302: 328-36 (2002)


Article DOI: 10.1124/jpet.302.1.328
BindingDB Entry DOI: 10.7270/Q2JQ0ZK1
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.15n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by PDSP Ki Database




J Pharmacol Exp Ther 311: 274-81 (2004)


Article DOI: 10.1124/jpet.104.070086
BindingDB Entry DOI: 10.7270/Q27S7MB9
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Homo sapiens (Human))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.65n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by PDSP Ki Database




J Pharmacol Exp Ther 302: 328-36 (2002)


Article DOI: 10.1124/jpet.302.1.328
BindingDB Entry DOI: 10.7270/Q2JQ0ZK1
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
2n/an/an/an/an/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Binding affinity to human histamine H3 receptor expressed in HEK293 cells


Bioorg Med Chem 23: 1588-600 (2015)


Article DOI: 10.1016/j.bmc.2015.01.060
BindingDB Entry DOI: 10.7270/Q2TF0010
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Homo sapiens (Human))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
2.5n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by PDSP Ki Database




J Pharmacol Exp Ther 302: 328-36 (2002)


Article DOI: 10.1124/jpet.302.1.328
BindingDB Entry DOI: 10.7270/Q2JQ0ZK1
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
30n/an/an/an/an/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Displacement of [3H]Mesulergine from human 5-HT2C-INI receptor expressed in HEK293 cells by scintillation counting analysis


Bioorg Med Chem 23: 1588-600 (2015)


Article DOI: 10.1016/j.bmc.2015.01.060
BindingDB Entry DOI: 10.7270/Q2TF0010
More data for this
Ligand-Target Pair
Serotonin receptor (2b and 2c)


(Homo sapiens (Human))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
94n/an/an/an/an/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293 cells by scintillation counting analysis


Bioorg Med Chem 23: 1588-600 (2015)


Article DOI: 10.1016/j.bmc.2015.01.060
BindingDB Entry DOI: 10.7270/Q2TF0010
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
100n/an/an/an/an/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5-HT2A receptor expressed in HEK293 cells by scintillation counting analysis


Bioorg Med Chem 23: 1588-600 (2015)


Article DOI: 10.1016/j.bmc.2015.01.060
BindingDB Entry DOI: 10.7270/Q2TF0010
More data for this
Ligand-Target Pair