BindingDB PrimarySearch

BDBM86143 L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH2::RFRP-3::RFamide-related peptide 3

SMILES: [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@@H](-[#7])-[#6](-[#6])-[#6])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O

InChI Key: InChIKey=JFZCLMZUABKABL-GVCDGELBSA-N

Data: 3 KI 2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 86143
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
NPFF (RAT)	BDBM86143 (L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Juvantia Pharma, Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 825-32 (2003) Article DOI: 10.1124/jpet.102.047118 BindingDB Entry DOI: 10.7270/Q2WS8RS2
Juvantia Pharma, Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
NPFF2 (Homo sapiens (Human))	BDBM86143 (L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Juvantia Pharma, Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 825-32 (2003) Article DOI: 10.1124/jpet.102.047118 BindingDB Entry DOI: 10.7270/Q2WS8RS2
Juvantia Pharma, Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
G-protein coupled receptor 10 (GPR10) (Homo sapiens (Human))	BDBM86143 (L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Juvantia Pharma, Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 825-32 (2003) Article DOI: 10.1124/jpet.102.047118 BindingDB Entry DOI: 10.7270/Q2WS8RS2
Juvantia Pharma, Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
NPFF2 (Homo sapiens (Human))	BDBM86143 (L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...				J Med Chem 55: 6124-36 (2012) Article DOI: 10.1021/jm300535s BindingDB Entry DOI: 10.7270/Q26974PV
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide FF receptor 1 (Homo sapiens (Human))	BDBM86143 (L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Agonist activity at human NPFF1 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...				J Med Chem 55: 6124-36 (2012) Article DOI: 10.1021/jm300535s BindingDB Entry DOI: 10.7270/Q26974PV
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair