Found 5 hits for monomerid = 86188 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hrh3 protein
(RAT) | BDBM86188
(CHEMBL366977 | SCH 79687)Show SMILES Clc1cc(Cl)cc(NC(=O)NCc2ccc(Cc3cnc[nH]3)cc2)c1 Show InChI InChI=1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 1037-44 (2003)
Article DOI: 10.1124/jpet.103.049254 BindingDB Entry DOI: 10.7270/Q24B2ZVV |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(GUINEA PIG) | BDBM86188
(CHEMBL366977 | SCH 79687)Show SMILES Clc1cc(Cl)cc(NC(=O)NCc2ccc(Cc3cnc[nH]3)cc2)c1 Show InChI InChI=1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25) | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Schering Plough Research Institute
Curated by ChEMBL
| Assay Description Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membrane |
Bioorg Med Chem Lett 12: 937-41 (2002)
BindingDB Entry DOI: 10.7270/Q2W37VN7 |
More data for this Ligand-Target Pair | |
Nischarin
(RAT) | BDBM86188
(CHEMBL366977 | SCH 79687)Show SMILES Clc1cc(Cl)cc(NC(=O)NCc2ccc(Cc3cnc[nH]3)cc2)c1 Show InChI InChI=1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25) | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 155 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 1037-44 (2003)
Article DOI: 10.1124/jpet.103.049254 BindingDB Entry DOI: 10.7270/Q24B2ZVV |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86188
(CHEMBL366977 | SCH 79687)Show SMILES Clc1cc(Cl)cc(NC(=O)NCc2ccc(Cc3cnc[nH]3)cc2)c1 Show InChI InChI=1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25) | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 1037-44 (2003)
Article DOI: 10.1124/jpet.103.049254 BindingDB Entry DOI: 10.7270/Q24B2ZVV |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86188
(CHEMBL366977 | SCH 79687)Show SMILES Clc1cc(Cl)cc(NC(=O)NCc2ccc(Cc3cnc[nH]3)cc2)c1 Show InChI InChI=1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25) | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 1037-44 (2003)
Article DOI: 10.1124/jpet.103.049254 BindingDB Entry DOI: 10.7270/Q24B2ZVV |
More data for this Ligand-Target Pair | |