BDBM86491 DiPOA::[8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic Acid

SMILES: OC(=O)CN1CN(c2ccccc2)C2(CCN(CCC(c3ccccc3)c3ccccc3)CC2)C1=O

InChI Key: InChIKey=BNMJRKJLCRSUJA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM86491 (DiPOA | [8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,...) Show SMILES OC(=O)CN1CN(c2ccccc2)C2(CCN(CCC(c3ccccc3)c3ccccc3)CC2)C1=O Show InChI InChI=1S/C30H33N3O3/c34-28(35)22-32-23-33(26-14-8-3-9-15-26)30(29(32)36)17-20-31(21-18-30)19-16-27(24-10-4-1-5-11-24)25-12-6-2-7-13-25/h1-15,27H,16-23H2,(H,34,35)	PDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	0.760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma Discovery Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 310: 783-92 (2004) Article DOI: 10.1124/jpet.103.063313 BindingDB Entry DOI: 10.7270/Q2J67FHD
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM86491 (DiPOA | [8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,...) Show SMILES OC(=O)CN1CN(c2ccccc2)C2(CCN(CCC(c3ccccc3)c3ccccc3)CC2)C1=O Show InChI InChI=1S/C30H33N3O3/c34-28(35)22-32-23-33(26-14-8-3-9-15-26)30(29(32)36)17-20-31(21-18-30)19-16-27(24-10-4-1-5-11-24)25-12-6-2-7-13-25/h1-15,27H,16-23H2,(H,34,35)	PDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	243	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma Discovery Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 310: 783-92 (2004) Article DOI: 10.1124/jpet.103.063313 BindingDB Entry DOI: 10.7270/Q2J67FHD
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM86491 (DiPOA | [8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,...) Show SMILES OC(=O)CN1CN(c2ccccc2)C2(CCN(CCC(c3ccccc3)c3ccccc3)CC2)C1=O Show InChI InChI=1S/C30H33N3O3/c34-28(35)22-32-23-33(26-14-8-3-9-15-26)30(29(32)36)17-20-31(21-18-30)19-16-27(24-10-4-1-5-11-24)25-12-6-2-7-13-25/h1-15,27H,16-23H2,(H,34,35)	PDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	286	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma Discovery Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 310: 783-92 (2004) Article DOI: 10.1124/jpet.103.063313 BindingDB Entry DOI: 10.7270/Q2J67FHD
					More data for this Ligand-Target Pair