BDBM86646 BC11-38-4::US9173884, BC11-38-4
SMILES: CCCSc1nc2CCSc2c(=O)n1-c1ccccc1OC
InChI Key: InChIKey=MXDVDZKXHJWBLR-UHFFFAOYSA-N
Data: 22 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase 11A (PDE11A) (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 2A (Rattus norvegicus) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-inhibited 3',5'-cyclic phosphodiesterase B (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 4A10 (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | MMDB B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 6C (PDE6C) (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 7 (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 8 (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 9A (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 11A (PDE11A) (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 2A (PDE2A2) (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 3 (PDE3) (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Isoform 4 (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 6C (PDE6C) (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 7 (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 8 (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 9A (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Boston College US Patent | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6... | US Patent US9173884 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM86646 (BC11-38-4 | US9173884, BC11-38-4) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College | Assay Description In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1... | Chem Biol 19: 155-63 (2012) Article DOI: 10.1016/j.chembiol.2011.12.010 BindingDB Entry DOI: 10.7270/Q2FB51JK | |||||||||||
More data for this Ligand-Target Pair |