Found 6 hits for monomerid = 86737 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H2 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86737
(UR-AK22)Show SMILES NC(NC(=O)CCCCc1ccccc1)=NCCCc1cnc[nH]1 |w:15.16| Show InChI InChI=1S/C18H25N5O/c19-18(21-12-6-10-16-13-20-14-22-16)23-17(24)11-5-4-9-15-7-2-1-3-8-15/h1-3,7-8,13-14H,4-6,9-12H2,(H,20,22)(H3,19,21,23,24) | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 317: 1262-8 (2006)
Article DOI: 10.1124/jpet.106.102897 BindingDB Entry DOI: 10.7270/Q2X63KHZ |
More data for this Ligand-Target Pair | |
Histamine H2 Receptor
(Homo sapiens (Human)) | BDBM86737
(UR-AK22)Show SMILES NC(NC(=O)CCCCc1ccccc1)=NCCCc1cnc[nH]1 |w:15.16| Show InChI InChI=1S/C18H25N5O/c19-18(21-12-6-10-16-13-20-14-22-16)23-17(24)11-5-4-9-15-7-2-1-3-8-15/h1-3,7-8,13-14H,4-6,9-12H2,(H,20,22)(H3,19,21,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 317: 1262-8 (2006)
Article DOI: 10.1124/jpet.106.102897 BindingDB Entry DOI: 10.7270/Q2X63KHZ |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86737
(UR-AK22)Show SMILES NC(NC(=O)CCCCc1ccccc1)=NCCCc1cnc[nH]1 |w:15.16| Show InChI InChI=1S/C18H25N5O/c19-18(21-12-6-10-16-13-20-14-22-16)23-17(24)11-5-4-9-15-7-2-1-3-8-15/h1-3,7-8,13-14H,4-6,9-12H2,(H,20,22)(H3,19,21,23,24) | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 317: 1262-8 (2006)
Article DOI: 10.1124/jpet.106.102897 BindingDB Entry DOI: 10.7270/Q2X63KHZ |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM86737
(UR-AK22)Show SMILES NC(NC(=O)CCCCc1ccccc1)=NCCCc1cnc[nH]1 |w:15.16| Show InChI InChI=1S/C18H25N5O/c19-18(21-12-6-10-16-13-20-14-22-16)23-17(24)11-5-4-9-15-7-2-1-3-8-15/h1-3,7-8,13-14H,4-6,9-12H2,(H,20,22)(H3,19,21,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 317: 1262-8 (2006)
Article DOI: 10.1124/jpet.106.102897 BindingDB Entry DOI: 10.7270/Q2X63KHZ |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86737
(UR-AK22)Show SMILES NC(NC(=O)CCCCc1ccccc1)=NCCCc1cnc[nH]1 |w:15.16| Show InChI InChI=1S/C18H25N5O/c19-18(21-12-6-10-16-13-20-14-22-16)23-17(24)11-5-4-9-15-7-2-1-3-8-15/h1-3,7-8,13-14H,4-6,9-12H2,(H,20,22)(H3,19,21,23,24) | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 562 | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced positive chronotropic activity |
J Med Chem 51: 7193-204 (2009)
Article DOI: 10.1021/jm800841w BindingDB Entry DOI: 10.7270/Q2RN38T6 |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86737
(UR-AK22)Show SMILES NC(NC(=O)CCCCc1ccccc1)=NCCCc1cnc[nH]1 |w:15.16| Show InChI InChI=1S/C18H25N5O/c19-18(21-12-6-10-16-13-20-14-22-16)23-17(24)11-5-4-9-15-7-2-1-3-8-15/h1-3,7-8,13-14H,4-6,9-12H2,(H,20,22)(H3,19,21,23,24) | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 468 | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activity |
J Med Chem 51: 7193-204 (2009)
Article DOI: 10.1021/jm800841w BindingDB Entry DOI: 10.7270/Q2RN38T6 |
More data for this Ligand-Target Pair | |